Document Detail

Pathologic features of placentas from singleton pregnancies obtained by in vitro fertilization and embryo transfer.
MedLine Citation:
PMID:  2359567     Owner:  NLM     Status:  MEDLINE    
Fifty placentas were collected at term from singleton pregnancies resulting from in vitro fertilization (IVF) and intrauterine embryo transfer. Their pathologic features were compared with those of a control group composed of 50 placentas obtained from spontaneous singleton pregnancies. The mean maternal age, mean gestational age, mean fetal weight, sex ratio, and rate of pregnancy complications did not differ. There was also no significant difference between the groups in the mean placental weight and in the incidence of placental pathologic lesions, including extended infarcts, massive perivillous fibrin depositions, chorioangiomas, and placental inflammatory lesions. The incidence of abnormal placental shapes was significantly (P less than .05) greater in the IVF group (22%) compared with the control group (6%). A significant (P less than .025) difference was observed between the groups in the distribution of umbilical cord insertions. The mean distance between the cord insertion and the closest placental margin was significantly (P less than .005) shorter in the group conceived by IVF (3.23 +/- 1.91 cm) than in the control group (4.54 +/- 2.42 cm). A relationship between these placental morphologic features and the superficial implantation and/or inadequate orientation of the blastocyst after IVF and intrauterine embryo transfer is proposed.
E Jauniaux; Y Englert; M Vanesse; M Hiden; P Wilkin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  76     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-07-31     Completed Date:  1990-07-31     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Academic Hospital Erasme, Belgium.
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MeSH Terms
Embryo Transfer*
Fertilization in Vitro*
Fibrin / analysis
Infarction / pathology
Organ Size
Placenta / blood supply,  pathology*
Umbilical Cord / pathology
Reg. No./Substance:

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