| Pathologic features of the lung in the acquired immune deficiency syndrome (AIDS): an autopsy study of seventeen homosexual males. | |
| | |
MedLine Citation:
|
PMID: 6318549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The lungs of 17 homosexual males who died of the acquired immune deficiency syndrome were studied to determine the type and extent of pulmonary disease present at autopsy. All patients had two or more pathologic processes, including one or more infections in their lungs. Cytomegalovirus pneumonia was the most common pulmonary infection identified at autopsy (15 patients) but was documented morphologically rarely during life (two patients). Most patients with Pneumocystis pneumonia had recurrent or persistent pneumocystosis. Although some of these individuals had evidence of early interstitial fibrosis, others showed complete resolution of the pulmonary changes. Diffuse alveolar damage was observed in 12 patients, and cytomegalovirus and/or Pneumocystis carinii was a likely etiologic agent in each instance. Mycobacterium avium-intracellulare infection was identified in four patients but was not associated with significant pulmonary alterations. Kaposi's sarcoma was found in the lungs of six patients. Early pulmonary involvement appeared as interstitial infiltrates with progression to nodular tumor masses obliterating the underlying lung. Pulmonary hemorrhage was an important complication of Kaposi's sarcoma involving the lung. |
| | |
Authors:
|
G Nash; S Fligiel |
Related Documents
:
|
436519 - Pulmonary manifestations in patients with malignant melanoma during bcg immunotherapy. ... 7564789 - Role of thrombin in pulmonary fibrosis. 19446279 - Role of endothelin-1 in acute lung injury. 17428649 - Two distinct clinical types of interstitial lung disease associated with polymyositis-d... 18454219 - Dyspnea, pulmonary function and exercise capacity in adult saudi patients with sickle c... 21039359 - A new non-radiological method to assess potential lung recruitability: a pilot study in... 16045099 - Perioperative anaesthetic management of a patient with relapsed aplastic anaemia. 10559569 - Dementia with leukoaraiosis: clinical differentiation by temporoparietal hypometabolism... 18229789 - The slow-brainstem syndrome: tinnitus and dyssynchrony in the central nervous system. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of clinical pathology Volume: 81 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 1984 Jan |
Date Detail:
|
Created Date: 1984-02-15 Completed Date: 1984-02-15 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 6-12 Citation Subset: AIM; IM; X |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acquired Immunodeficiency Syndrome
/
pathology* Adult Autopsy Cytomegalovirus Infections / pathology Hemorrhage / pathology Homosexuality* Humans Lung / pathology* Lung Neoplasms / pathology Male Mycobacterium Infections, Atypical / pathology Pneumonia, Pneumocystis / pathology Pulmonary Alveoli / pathology Sarcoma, Kaposi / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Breast carcinoma with osseous metaplasia: an electron microscopic study.
Next Document: Small cell carcinoma of the endometrium in a 23-year-old woman: light microscopic and ultrastructura...