Document Detail


Pathologic evidence of extensive left ventricular involvement in arrhythmogenic right ventricular cardiomyopathy.
MedLine Citation:
PMID:  1644439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arrhythmogenic right ventricular cardiomyopathy (also known as arrhythmogenic right ventricular dysplasia) is characterized by adipose or fibroadipose tissue replacement of the right ventricular myocardium, whereas the left ventricle is substantively spared. Two cases of the disease with evidence of extensive left ventricular involvement at pathologic examination are described. Hearts from two patients who died suddenly showed full-thickness right ventricular fatty infiltration associated with extensive left ventricular involvement (greater than 50% of myocardial thickness). These findings might explain the reported clinical features of left ventricle dysfunction in a subset of patients with arrhythmogenic right ventricular cardiomyopathy. In view of the biventricular involvement of the disease, it should simply be termed "arrhythmogenic cardiomyopathy."
Authors:
P Gallo; G d'Amati; F Pelliccia
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  23     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-09-08     Completed Date:  1992-09-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  948-52     Citation Subset:  IM    
Affiliation:
Department of Experimental Medicine, University of L'Aquila, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / pathology
Adult
Arrhythmias, Cardiac / pathology*
Autopsy
Cardiomyopathies / pathology*
Heart Ventricles / pathology
Humans
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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