Document Detail

Pathologic nipple discharge in patients with radiologically invisible mass: review of 28 consecutive sub-areolar explorations.
MedLine Citation:
PMID:  19645776     Owner:  NLM     Status:  MEDLINE    
The carcinoma frequency of clinically and radiologically negative pathologic nipple discharges (PNDs) and the optimum management strategy of these cases are still unclear. In this study, the frequency of cancer and the situation of the classic surgical intervention in patients with PND and invisible mammographic and ultrasonographic results are reviewed. The data pertaining to the cases of sub-areolar exploration and major duct excision in a surgery clinic of university hospital from December 2002 to June 2007 have been examined in detail. In 28 cases with PND, which did not have any findings during conventional radiologic examinations, 21% of cases had malignant, and 7% of cases had atypical ductal hyperplasia. The frequency of invasive or in situ carcinoma is not low in clinically and radiologically negative PNDs. Sub-areolar exploration and major duct excision seems to be an appropriate and definitive diagnostic and therapeutic option in this special patient group.
Mehmet Ali Kocdor; Ali Ibrahim Sevinc; Tulay Canda; Pinar Balci; Serdar Saydam; Ozgur Cavdaroglu; Omer Harmancioglu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The breast journal     Volume:  15     ISSN:  1524-4741     ISO Abbreviation:  Breast J     Publication Date:    2009 May-Jun
Date Detail:
Created Date:  2009-08-03     Completed Date:  2009-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505539     Medline TA:  Breast J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  230-5     Citation Subset:  IM    
Department of Surgery, Dokuz Eylul University School of Medicine, Izmir, Turkey.
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MeSH Terms
Biopsy, Fine-Needle
Breast Diseases / pathology,  radiography
Breast Neoplasms / pathology,  radiography*,  secretion*
Carcinoma, Ductal, Breast / pathology,  radiography*,  secretion*
Carcinoma, Intraductal, Noninfiltrating / pathology,  radiography,  secretion
Exudates and Transudates
Mammography / methods
Middle Aged
Neoplasms, Unknown Primary / pathology,  radiography
Nipples / pathology,  radiography*,  secretion*
Precancerous Conditions* / pathology
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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