Document Detail


Pathogenicity of Isospora suis in gnotobiotic and conventionalised piglets.
MedLine Citation:
PMID:  4024419     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Isospora suis is unequivocally a primary pathogen of swine. Inoculation of I suis in conventionalised and germ-free piglets caused a biphasic disease course with marked diarrhoea, villous atrophy and necrosis of the intestinal epithelium at four to six and eight to 10 days after inoculation. The presence of a normal bacterial flora markedly (P less than 0.05) influenced the survival rate of piglets but did not appear to affect the histopathological changes observed. Mild limited focal necrosis and bile stasis were present in the liver at eight to 10 days after inoculation. In this period there was also ectasia of lymph vessels in the intestinal lymph nodes.
Authors:
J H Harleman; R C Meyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  116     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-09-04     Completed Date:  1985-09-04     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  561-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Coccidiosis / pathology,  veterinary*
Germ-Free Life*
Intestinal Mucosa / pathology
Intestine, Small / pathology
Isospora / pathogenicity*
Jejunum / pathology
Liver / pathology
Lymph Nodes / pathology
Swine / microbiology*
Swine Diseases / microbiology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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