| Pathogenetic mechanisms of exercise-induced asthma and the refractory period. | |
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MedLine Citation:
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PMID: 3045523 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exercise is a powerful stimulus to the development of asthma. In most asthmatic subjects the airways obstruction recovers spontaneously within 60 minutes, but in some subjects there is more prolonged airflow obstruction which requires bronchodilator treatment. Approximately 40-50% of subjects with EIA will show a refractory period of two to four hours after an initial exercise task, during which time an identical exercise task will evoke significantly less (less than 50%) bronchoconstriction. In some patients, particularly children, EIA will be followed three to nine hours later by a further episode of bronchospasm, termed the late asthmatic response. There remains considerable debate about the pathogenesis of EIA the refractory period and the late asthmatic response. |
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Authors:
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N G Belcher; S O'Hickey; J P Arm; T H Lee |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: New England and regional allergy proceedings Volume: 9 ISSN: 0742-2814 ISO Abbreviation: N Engl Reg Allergy Proc Publication Date: 1988 May-Jun |
Date Detail:
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Created Date: 1988-10-03 Completed Date: 1988-10-03 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8306562 Medline TA: N Engl Reg Allergy Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 199-201 Citation Subset: IM |
Affiliation:
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Department of Medicine, Guy's Hospital, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asthma
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etiology* Asthma, Exercise-Induced / etiology* Humans Physical Exertion Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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