Document Detail

Pathogenesis of pulmonary infarction.
MedLine Citation:
PMID:  6462058     Owner:  NLM     Status:  MEDLINE    
Pulmonary embolism discovered at autopsy is still as prevalent as previously reported in the last three to four decades. Only a certain percentage of pulmonary emboli result in pulmonary infarction. Recently published studies have suggested that importance of the size of the occluded pulmonary artery in the occurrence of infarction. Our study of 45 autopsy subjects in which there were pulmonary emboli shows a 31 percent incidence of pulmonary artery branches of 3 mm in diameter or less, but emboli in larger arteries may show frequent extensions into their smaller distal branches without producing infarct. Pulmonary infarction also occurs more commonly in patients dying of cardiovascular or malignant diseases than it does in those dying of other diseases, and the combination of shock and congestive left heart failure appears to be the most significant hemodynamic risk factor in the development of pulmonary infarction. However, the increased risk of pulmonary infarction in patients with malignancy may not be accounted for by the existence of these two hemodynamic risk factors alone.
M S Tsao; D Schraufnagel; N S Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of medicine     Volume:  72     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-06-24     Completed Date:  1982-06-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  599-606     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiomegaly / complications
Lung / blood supply
Neoplasms / complications
Pulmonary Embolism / epidemiology,  etiology*,  pathology
Shock / complications

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