Document Detail

Pathogenesis of liver lesions in mice following a primary infection with Ascaris suum.
MedLine Citation:
PMID:  7292896     Owner:  NLM     Status:  MEDLINE    
The development of liver lesions in mice infected with Ascaris suum is described and compared to the lesions in pigs. The findings suggest that liver necroses in mice are initially periacinar (centrilobular), caused by anoxia resulting from a vascular obstruction by the A. suum larvae located in the sinusoids; and that the lesions in pigs following a primary infection have a different pathogenesis. It is concluded that mice are unsuitable models for studying the pathogenesis of A. suum-induced liver lesions in pigs.
E Bindseil
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Veterinary pathology     Volume:  18     ISSN:  0300-9858     ISO Abbreviation:  Vet. Pathol.     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1981-12-21     Completed Date:  1981-12-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0312020     Medline TA:  Vet Pathol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  804-12     Citation Subset:  IM    
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MeSH Terms
Anoxia / complications
Ascariasis / etiology,  pathology,  veterinary*
Liver / pathology*
Liver Diseases, Parasitic / pathology,  veterinary
Mice, Inbred Strains
Species Specificity
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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