| Pathogenesis, investigation and dietary and medical management of gastroparesis. | |
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MedLine Citation:
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PMID: 21777300 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Delayed gastric emptying (gastroparesis) is associated with significant morbidity and, occasionally, mortality; clinicians therefore need a high index of suspicion to avoid missing the diagnosis. This review discusses the aetiology, diagnostic criteria and investigations pertinent to gastroparesis, and also critically reviews the evidence for nutritional and medical management strategies. Dietary manipulation plays a key role in management, and simple adjustment to meal routines and diets can lead to an improvement in symptoms, whereas alternative feeding routes play an important role in more severe cases. The role of pharmaceutical intervention is less clear; prokinetics and antiemetics are often prescribed; however, evidence for their efficacy is lacking, whereas gastric electric stimulation has an evolving role in the management of patients with symptoms refractory to medical therapies. The optimal treatment of gastroparesis would be to resolve symptoms and normalise gastric emptying times, and this may be achieved with future treatments that target the underlying pathology. For most patients with mild to moderate disease, dietary intervention plays a central role in the management of gastroparesis. |
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Authors:
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R Keld; L Kinsey; V Athwal; S Lal |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-21 |
Journal Detail:
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Title: Journal of human nutrition and dietetics : the official journal of the British Dietetic Association Volume: - ISSN: 1365-277X ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904840 Medline TA: J Hum Nutr Diet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 The Authors. Journal of Human Nutrition and Dietetics © 2011 The British Dietetic Association Ltd. |
Affiliation:
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Intestinal Failure Unit, Salford Royal Hospital and Salford University, Salford, UK Dietetic Department, Manchester Royal Infirmary, Manchester, UK Department of Medicine, Manchester University, Manchester, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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