Document Detail


Pathogenesis of dry eye in leprosy and tear functions.
MedLine Citation:
PMID:  11875765     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Seventy-five leprosy patients and an equal number of age- and sex-matched controls were examined for tear functions, using Schirmer's test and tear break up time (BUT). There was no statistically significant difference in the Schirmer's test, but the tear BUT showed a statistically significant lower value of < 10 seconds in multibacillary patients compared to paucibacillary patients. Leprosy patients with lagophthalmos and decreased corneal sensation showed a lower value of tear BUT which was also statistically significant. This study shows that even though the quantity of tears is not affected, proper and prolonged wetting of the cornea is deficient in many leprosy patients.
Authors:
S Koshy; E Daniel; N Kurian; P Yovan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association     Volume:  69     ISSN:  0148-916X     ISO Abbreviation:  Int. J. Lepr. Other Mycobact. Dis.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2002-03-05     Completed Date:  2002-03-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8505819     Medline TA:  Int J Lepr Other Mycobact Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  215-8     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Schieffelin Leprosy Research and Training Center, Karigari, Vellore District, Tamil Nadu, India 632 106. sthoppuram@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
Dry Eye Syndromes / etiology*,  physiopathology
Female
Humans
Leprosy / complications*,  physiopathology
Male
Prospective Studies
Tears / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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