Document Detail


Paternal race is a risk factor for preterm birth.
MedLine Citation:
PMID:  17689630     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to test the hypothesis that paternal race influences the risk for preterm birth. STUDY DESIGN: We conducted a population-based cohort study to examine the association of paternal race with preterm birth using the Missouri Department of Health's birth registry from 1989-1997. Birth outcomes were analyzed in 4 categories: white mother/white father, white mother/black father, black mother/white father, and black mother/ black father. RESULTS: We evaluated 527,845 birth records. The risk of preterm birth at <35 weeks of gestation increased when either parent was black (white mother/black father: adjusted odds ratio, 1.28 [95% CI, 1.13, 1.46], black mother/white father: adjusted odds ratio, 2.10 [95% CI, 1.68, 2.62], and black mother/black father: adjusted odds ratio, 2.28 [95% CI, 2.18, 2.39]) and was even higher for extreme preterm birth (<28 weeks of gestation) in pregnancies with a nonwhite parent. CONCLUSION: Paternal black race is associated with an increased risk of preterm birth in white mothers, which suggests a paternal contribution to fetal genotype that ultimately influences the risk for preterm delivery.
Authors:
Lisanne Palomar; Emily A DeFranco; Kirstin A Lee; Jenifer E Allsworth; Louis J Muglia
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  197     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-10     Completed Date:  2007-08-23     Revised Date:  2008-05-27    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  152.e1-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
African Continental Ancestry Group
Cohort Studies
Fathers
Female
Humans
Infant, Newborn
Male
Obstetric Labor, Premature / epidemiology,  ethnology,  etiology*
Pregnancy
Retrospective Studies
Risk Factors
Comments/Corrections
Comment In:
Am J Obstet Gynecol. 2008 Apr;198(4):485; author reply 483-4   [PMID:  18177831 ]
Am J Obstet Gynecol. 2008 Apr;198(4):483; author reply 483-4   [PMID:  18221929 ]
Am J Obstet Gynecol. 2008 Apr;198(4):484; author reply 483-4   [PMID:  18395050 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary human immunodeficiency virus infection during pregnancy detected by repeat testing.
Next Document:  Planned vs emergent cesarean hysterectomy.