| Paternal contribution to fetal alcohol syndrome. | |
| | |
MedLine Citation:
|
PMID: 15223537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Maternal alcohol use during pregnancy is associated with a wide range of adverse outcomes for the child. Many women who drink during pregnancy also have male partners who abuse alcohol. Existing data on paternal effects of alcohol abuse during the preconceptual period and at the time of conception are reviewed. Epidemiological data offer some support for a paternal influence on birth weight, congenital heart defects, and some evidence of mild cognitive impairments. Animal data have demonstrated decreased litter size, increased prevalence of low birth weight fetuses and mixed data on risk of malformations. Increased susceptibility to Pseudomonas bacterial infection has been reported. Cognitive and behavioral findings are the most robust effects. These include learning and memory deficits, hyperactivity, and poor stress tolerance. Multiple causal mechanisms for a paternal effect have been suggested, but none seems satisfactory to explain all findings. Further research is needed on paternal effects in animals and human populations. The results of this research may influence prevention activities. |
| | |
Authors:
|
Ernest Abel |
Related Documents
:
|
7871487 - Effects of static and time-varying (50-hz) magnetic fields on reproduction and fetal de... 3263247 - Cocaine exposure in a term neonate. necrotizing enterocolitis as a complication. 6538947 - Effects on the postnatal development of the mouse of preconception, postconception and/... 18708087 - Alcohol consumption behavior of pregnant women in japan. 10365567 - A survey of under-18 year old and 20-29 year old primigravidae delivered at the port mo... 17545557 - Stability of the m.8993t->g mtdna mutation load during human embryofetal development ha... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Addiction biology Volume: 9 ISSN: 1355-6215 ISO Abbreviation: Addict Biol Publication Date: 2004 Jun |
Date Detail:
|
Created Date: 2004-06-29 Completed Date: 2004-10-21 Revised Date: 2007-03-27 |
Medline Journal Info:
|
Nlm Unique ID: 9604935 Medline TA: Addict Biol Country: England |
Other Details:
|
Languages: eng Pagination: 127-33; discussion 135-6 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA. eabel@wayne.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Alcoholism
/
complications Female Fetal Alcohol Syndrome / etiology, physiopathology* Humans Maternal Behavior / psychology Parents* Pregnancy Prenatal Exposure Delayed Effects |
| Comments/Corrections | |
Comment In:
|
Addict Biol. 2004 Jun;9(2):135-6
[PMID:
15223538
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fetal alcohol syndrome through the eyes of parents.
Next Document: Fetal alcohol syndrome at the cellular level.