Document Detail


Patents of bio-active compounds based on computer-aided drug discovery techniques .
MedLine Citation:
PMID:  23276997     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In recent times, there has been an increased use of Computer-Aided Drug Discovery (CADD) techniques in Medicinal Chemistry as auxiliary tools in drug discovery. Whilst the ultimate goal of Medicinal Chemistry research is for the discovery of new drug candidates, a secondary yet important outcome that results is in the creation of new computational tools. This process is often accompanied by a lack of understanding of the legal aspects related to software and model use, that is, the copyright protection of new medicinal chemistry software and software-mediated discovered products. In the center of picture, which lies in the frontiers of legal, chemistry, and biosciences, we found computational modeling-based drug discovery patents. This article aims to review prominent cases of patents of bio-active organic compounds that involved/protect also computational techniques. We put special emphasis on patents based on Quantitative Structure-Activity Relationships (QSAR) models but we include other techniques too. An overview of relevant international issues on drug patenting is also presented.
Authors:
Francisco Prado-Prado; Xerardo Garcia-Mera; Jose Enrique Rodriguez-Borges; Riccardo Concu; Lazaro Guillermo Perez-Montoto; Humberto Gonzalez-Diaz; Aliuska Duardo-Sanchez
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Publication Detail:
Type:  Journal Article     Date:  2013-01-01
Journal Detail:
Title:  Frontiers in bioscience (Elite edition)     Volume:  5     ISSN:  1945-0508     ISO Abbreviation:  Front Biosci (Elite Ed)     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485240     Medline TA:  Front Biosci (Elite Ed)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  399-407     Citation Subset:  IM    
Affiliation:
Department of Especial Public Law, Faculty of Law, University of Santiago de Compostela, 15782, Spain.
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