Document Detail


Patent foramen ovale closure using a bioabsorbable closure device: safety and efficacy at 6-month follow-up.
MedLine Citation:
PMID:  20850098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The aim of this study was to assess the mid-term safety and efficacy of percutaneous patent foramen ovale (PFO) closure using a bioabsorbable device (BioSTAR, NMT Medical, Boston, Massachusetts).
BACKGROUND: Closure of PFO in patients with cryptogenic stroke has proven to be safe and effective using different types of permanent devices.
METHODS: All consecutive patients who underwent percutaneous PFO closure with the bioabsorbable closure device between November 2007 and January 2009 were included. Residual shunt was assessed using contrast transthoracic echocardiography.
RESULTS: Sixty-two patients (55% women, mean age 47.7 ± 11.8 years) underwent PFO closure. The in-hospital complications were a surgical device retrieval in 2 patients (3.2%), device reposition in 1 (1.6%), and a minimal groin hematoma in 6 patients (9.7%). The short-term complications at 1-month follow-up (n = 60) were a transient ischemic attack in the presence of a residual shunt in 1 patient and new supraventricular tachycardia in 7 patients (11.3%). At 6-month follow-up (n = 60), 1 patient without residual shunt developed a transient ischemic attack and 1 developed atrial fibrillation. A mild or moderate residual shunt was noted in 51.7%, 33.9%, and 23.7% after 1-day, 1-month, and 6-month follow-up, respectively. A large shunt was present in 8.3%, 3.4%, and 0% after 1-day, 1-month, and 6-month follow-up.
CONCLUSIONS: Closure of PFO using the bioabsorbable device is associated with a low complication rate and a low recurrence rate of embolic events. However, a relatively high percentage of mild or moderate residual shunting is still present at 6-month follow-up.
Authors:
Ben J Van den Branden; Martijn C Post; Herbert W Plokker; Jurriën M ten Berg; Maarten J Suttorp
Related Documents :
10598708 - A randomized, controlled study of a programmable shunt valve versus a conventional valv...
15221248 - Changes in ventricular volume in hydrocephalic children following successful endoscopic...
23702318 - The impact of a patient's age on the clinical presentation of inflammatory paranasal si...
16048288 - Endoscopic third ventriculostomy for hydrocephalus associated with tectal gliomas.
19083538 - Pain control in augmentation mammaplasty: safety and efficacy of indwelling catheters i...
19686438 - Efficacy and safety of boosted and unboosted atazanavir-containing antiretroviral regim...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  JACC. Cardiovascular interventions     Volume:  3     ISSN:  1876-7605     ISO Abbreviation:  JACC Cardiovasc Interv     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-20     Completed Date:  2011-03-01     Revised Date:  2014-09-05    
Medline Journal Info:
Nlm Unique ID:  101467004     Medline TA:  JACC Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  968-73     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Absorbable Implants*
Aged
Cardiac Surgical Procedures / instrumentation*
Echocardiography
Female
Follow-Up Studies
Foramen Ovale, Patent / diagnosis,  surgery*
Humans
Male
Middle Aged
Radiography, Thoracic
Retrospective Studies
Septal Occluder Device*
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Patent foramen ovale closure with the SeptRx device initial experience with the first "In-Tunnel" de...
Next Document:  Reparative effects of allogeneic mesenchymal precursor cells delivered transendocardially in experim...