Document Detail

Patent ductus arteriosus equipment and technique. Amplatzer duct occluder: intermediate-term follow-up and technical considerations.
MedLine Citation:
PMID:  12053313     Owner:  NLM     Status:  MEDLINE    
Between May 1997 and June 2000, 69 patients, ages 0.1 to 34 years, underwent attempted anterograde transcatheter closure of a patent ductus arteriosus (PDA) using the Amplatzer Duct Occluder (ADO). The ADO is a cone-shaped, self-centering, and repositionable occluder made of nitinol wire mesh. A 5Fr to 7Fr sheath was used for the delivery of the device. The mean PDA diameter (at the pulmonary end) was 4.6 +/- 1.9 mm (range 1 mm-8.5 mm). Sixty-seven of the 69 patients had successful device placement. The mean ADO smallest diameter was 6.9 +/- 1.8 mm (range 4 mm-12 mm). Complete angiographic closure occurred in 62 (92.5%) of 67 patients (95% confidence interval, 88.22%-98.77%). In five patients, there was a trivial residual shunt immediately after the procedure. At 24 hours, color Doppler flow imaging revealed complete closure in all 67 (100%) patients. The unsuccessful attempts occurred in two patients with a small, 1-mm diameter native PDA and residual PDA after surgical occlusion. Fluoroscopy time was 7.6 +/- 1.8 minutes (4 min-18 min). No complications were observed. At a median follow-up of 1.5 years (range 0.25 to 3.2 years), all patients had complete closure without complications. We conclude that transcatheter closure using the ADO is a highly effective and safe treatment for most patients with PDA.
B D Thanopoulos; F A Hakim; A Hiari; G S Tsaousis; C Paphitis; Z M Hijazi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  14     ISSN:  0896-4327     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2002-06-10     Completed Date:  2002-06-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-54     Citation Subset:  IM    
Department of Pediatric Cardiology, Aghia Sophia Children's Hospital, Thivon & Levadias Street, 115 27 Athens, Greece.
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MeSH Terms
Child, Preschool
Ductus Arteriosus, Patent / therapy*
Embolization, Therapeutic / instrumentation*,  methods*
Equipment Design
Follow-Up Studies
Infant, Newborn

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