| Patent ductus arteriosus ligation and post-operative hemodynamic instability: case report and framework for enhanced neonatal care. | |
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MedLine Citation:
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PMID: 20740386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ligation of a patent ductus arteriosus can lead to severe cardiorespiratory compromise in preterm infants. This report reviews the postoperative course of a patient with significant cardiorespiratory instability following surgical ligation of the patent ductus arteriosus and presents a framework for enhanced cardiovascular care in this population. A preterm infant, born at 24 wk gestation underwent ligation of a large haemodynamically significant ductus arteriosus after failure of 2 courses of indomethacin. He developed systemic hypotension, which was aggressively treated with high doses of multiple cardiotropic agents. After 10 hr of refractory hypotension, the addition of hydrocortisone normalized blood pressure. This article outlines preprocedural categorization of infants according to ductal illness severity which facilitates the risk assignment for postoperative deterioration, development of clinical guidelines specific to the likely haemodynamic changes, enhanced role of functional echocardiography for guiding therapy, and interprofessional education. |
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Authors:
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Arvind Sehgal; Johny Vakayil Francis; Andrew James; Patrick J McNamara |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-08-26 |
Journal Detail:
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Title: Indian journal of pediatrics Volume: 77 ISSN: 0973-7693 ISO Abbreviation: Indian J Pediatr Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2011-08-05 Completed Date: 2012-03-20 Revised Date: 2012-08-31 |
Medline Journal Info:
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Nlm Unique ID: 0417442 Medline TA: Indian J Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 905-7 Citation Subset: IM |
Affiliation:
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Monash Newborn, Monash Children's, VIC, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ductus Arteriosus, Patent
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surgery* Hemodynamics Humans Hypotension / etiology*, therapy Infant, Newborn Infant, Premature Infant, Premature, Diseases / surgery* Ligation Male Postoperative Care Postoperative Complications* / therapy |
| Comments/Corrections | |
Comment In:
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Indian J Pediatr. 2012 Apr;79(4):543-4
[PMID:
21769522
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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