| Patch testing with formaldehyde and formaldehyde-releasers: multicentre study in Spain (2005-2009). | |
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MedLine Citation:
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PMID: 21767276 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background. Formaldehyde and formaldehyde-releasers are common causes of allergic contact dermatitis. Objectives. To determine the frequency of sensitization to formaldehyde and seven formaldehyde-releasers. To establish and characterize groups of patients according to the results of patch testing. Materials and methods. We performed a 5-year retrospective study, in six Spanish hospitals, of patients with positive patch test reactions to formaldehyde or any of seven formaldehyde-releasers. Results. The most frequent allergens were formaldehyde (1.72%), imidazolidinyl urea (1.05%), quaternium-15 (0.88%), and diazolidinyl urea (0.79%). Patients with sensitization to only formaldehyde had a higher frequency of occupational dermatitis (25%) than patients with sensitization to only formaldehyde-releasers (9.5%). The most common sites of dermatitis were the hands (31.7%) in patients with sensitization to only formaldehyde and the face and legs (31.3% and 24.6%) in patients with sensitization to only formaldehyde-releasers. We found a subgroup of 25 patients who were sensitized to both imidazolidinyl urea and diazolidinyl urea, and only 6 of these (24%) were also sensitized to formaldehyde. Conclusions. The inclusion of imidazolidinyl urea and diazolidinyl urea in the baseline series of the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) should enable better classification of patients allergic to formaldehyde, and could aid in their management. |
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Authors:
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Nuria Latorre; Leopoldo Borrego; Virginia Fernández-Redondo; Begoña García-Bravo; Ana María Giménez-Arnau; Javier Sánchez; Juan Francisco Silvestre |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-18 |
Journal Detail:
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Title: Contact dermatitis Volume: - ISSN: 1600-0536 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-7-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7604950 Medline TA: Contact Dermatitis Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 John Wiley & Sons A/S. |
Affiliation:
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Department of Dermatology, Hospital General Universitario de Alicante, 03010 Alicante, Spain Department of Dermatology, Hospital Insular de Las Palmas, Las Palmas de Gran Canaria, 35016, Spain Department of Dermatology, Hospital Gil Casares, Santiago de Compostela, 15706, Spain Department of Dermatology, Hospital Virgen de la Macarena, 41009 Sevilla, Spain Department of Dermatology, Hospital del Mar, 08003 Barcelona, Spain Department of Dermatology, Hospital La Princesa, 28005 Madrid, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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