Document Detail


Patch testing and aeroallergen intradermal testing in suspected allergic contact dermatitis, unclassified endogenous eczema and non-atopic chronic urticaria.
MedLine Citation:
PMID:  11553117     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the significance of contact allergen and aeroallergen sensitization in suspected allergic contact dermatitis (ACD), unclassified endogenous eczema (UEE) and non-atopic chronic urticaria (NACU). 63 cases of suspected ACD, 140 cases of suspected UEE and 21 cases of suspected NACU were patch tested with the standard series of Beijing Medical University and, if available, suspected materials as is. 22 such cases of ACD, 104 such cases of UEE and 42 such cases of NACU were intradermally tested with common aeroallergens. Patients with non-allergic skin disease served as controls. 85.7% of the suspected ACD patients, 57.9% of the suspected UEE patients and 52.4% of the suspected NACU patients were positive on patch testing, and the results in 81.0% of the suspected ACD patients and 23.6% of the suspected UEE patients were considered relevant. No patch test reactions in the NACU patients were considered relevant. 27.1% of the suspected UEE patients, 41.3% of the suspected ACD patients and 14.3% of the suspected NACU patients reacted to 2 or more contact allergens. High positive rates on aeroallergen intradermal testing were also found in suspected NACU (69.0%), UEE (49.0%) and ACD (59.1%) patients. These results support the conclusions that patients with allergic skin diseases will develop multiple sensitization, and that early detection and avoidance of sensitizing allergens is necessary. The exact rôle of aeroallergen sensitization in these diseases needs further study.
Authors:
L F Li; J Wang
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  45     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-09-12     Completed Date:  2003-01-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  84-8     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Peking University, The Third Hospital, Beijing, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Air Pollutants / adverse effects*
Allergens / adverse effects*
Case-Control Studies
Dermatitis, Allergic Contact / diagnosis*,  immunology,  pathology
Eczema / diagnosis,  immunology,  pathology
Female
Humans
Intradermal Tests / standards*
Male
Patch Tests / standards*
Predictive Value of Tests
Urticaria / diagnosis,  immunology,  pathology
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Allergens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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