Document Detail

Patch annulo-aortoplasty in an adult patient with congenital supravalvular aortic stenosis and a small aortic annulus.
MedLine Citation:
PMID:  21850585     Owner:  NLM     Status:  In-Data-Review    
A 39-year-old woman with familial homozygous hypercholesterolemia had supravalvular and valvular aortic stenosis. Modified Nick's procedure and aortic valve replacement was performed to relieve both the supravalvular and annular stenoses. At surgery, the ascending aorta was found to be narrowing at the level of the sinotubular junction, which was compatible with congenital supravalvular aortic stenosis. Histological examination of the aortic cusps showed sclerotic change due to hypercholesterolemia. These findings indicated that familial homozygous hypercholesterolemia caused valvular aortic stenosis and exacerbated congenital supravalvular aortic stenosis.
Naoto Morimoto; Keisuke Morimoto; Yoshihisa Morimoto; Akiko Tanaka; Toshihito Sakamoto; Kenji Okada; Yutaka Okita
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Publication Detail:
Type:  Journal Article     Date:  2011-08-18
Journal Detail:
Title:  General thoracic and cardiovascular surgery     Volume:  59     ISSN:  1863-6713     ISO Abbreviation:  Gen Thorac Cardiovasc Surg     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101303952     Medline TA:  Gen Thorac Cardiovasc Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  569-71     Citation Subset:  IM    
Department of Cardiovascular Surgery, Himeji Cardiovascular Center, 520 Saisho-ko, Himeji, Hyogo, 670-0981, Japan,
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