Document Detail


The patatin-containing phospholipase A pPLAIIα modulates oxylipin formation and water loss in Arabidopsis thaliana.
MedLine Citation:
PMID:  22259021     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The patatin-related phospholipase A (pPLA) hydrolyzes membrane glycerolipids to produce monoacyl compounds and free fatty acids. Phospholipids are cleaved by pPLAIIα at the sn-1 and sn-2 positions, and galactolipids, including those containing oxophytodienoic acids, can also serve as substrates. Ablation of pPLAIIα decreased lysophosphatidylcholine and lysophosphatidylethanolamine levels, but increased free linolenic acid. pPLAIIα-deficient plants displayed a higher level of jasmonic acid and methyl jasmonate, as well as the oxylipin-biosynthetic intermediates 13-hydroperoxylinolenic acid and 12-oxophytodienoic acid than wild-type (WT) plants. The expression of genes involved in oxylipin production was also higher in the pPLAIIα-deficient mutant than in WT plants. The mutant plants lost water more quickly than WT plants. The stomata of WT and mutant plants responded similarly to abscisic acid. In response to desiccation, the mutant and WT leaves produced abscisic acid at the same rate, but, after 4 h of desiccation, the jasmonic acid level was much higher in mutant than WT leaves. These results indicate that pPLAIIα negatively regulates oxylipin production and suggest a role in the removal of oxidatively modified fatty acids from membranes.
Authors:
Wen-Yu Yang; Yong Zheng; Sung Chul Bahn; Xiang-Qing Pan; Mao-Yin Li; Hieu Sy Vu; Mary R Roth; Brad Scheu; Ruth Welti; Yue-Yun Hong; Xue-Min Wang
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-01-18
Journal Detail:
Title:  Molecular plant     Volume:  5     ISSN:  1752-9867     ISO Abbreviation:  Mol Plant     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-23     Completed Date:  2012-07-17     Revised Date:  2013-04-15    
Medline Journal Info:
Nlm Unique ID:  101465514     Medline TA:  Mol Plant     Country:  England    
Other Details:
Languages:  eng     Pagination:  452-60     Citation Subset:  IM    
Affiliation:
Department of Biology, University of Missouri, St Louis, MO 63121, USA.
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MeSH Terms
Descriptor/Qualifier:
Abscisic Acid / pharmacology
Arabidopsis / drug effects,  enzymology*,  genetics
Arabidopsis Proteins / genetics,  metabolism*
Cyclopentanes / metabolism
Droughts
Galactolipids / metabolism
Gene Expression Regulation, Plant / drug effects
Gene Knockout Techniques
Hydrolysis / drug effects
Lysophospholipids / metabolism
Oxidation-Reduction / drug effects
Oxylipins / metabolism*
Phenotype
Phospholipases A / genetics,  metabolism*
Plant Leaves / drug effects,  metabolism
Plant Stomata / drug effects,  physiology
Substrate Specificity / drug effects
Up-Regulation / drug effects
Water / metabolism*
Grant Support
ID/Acronym/Agency:
P20 RR-016475/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Arabidopsis Proteins; 0/Cyclopentanes; 0/Galactolipids; 0/Lysophospholipids; 0/Oxylipins; 0/pPLAIIalpha protein, Arabidopsis; 21293-29-8/Abscisic Acid; 6RI5N05OWW/jasmonic acid; 7732-18-5/Water; EC 3.1.1.-/Phospholipases A
Comments/Corrections

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