Document Detail

Past and present preferred prescribing practices of hormone replacement therapy among Los Angeles gynecologists: possible implications for public health.
MedLine Citation:
PMID:  3354733     Owner:  NLM     Status:  MEDLINE    
Usual prescribing strategies of hormone replacement therapy for postmenopausal women by Los Angeles area gynecologists, both now and 10 years ago, were investigated by a mail survey. Of the 330 gynecologists who responded, estrogen therapy is currently used as a routine by nearly all (95 per cent), for women both with and without a uterus. Over three-fourths of these physicians favor use of 0.625 mg of conjugated equine estrogen. The estrogen is combined with cyclic progestin therapy, usually 10 mg of medroxyprogesterone acetate, by 86 per cent of gynecologists using estrogen for women with a uterus, and by 47 per cent for women without a uterus. Although conjugated equine estrogens were used widely for both groups of patients 10 years ago, a higher dose generally was preferred. Use of progestin therapy was uncommon (less than 20 per cent) for any postmenopausal patients at that time. Although the most common monthly therapeutic regimen for estrogen/progestin therapy is estrogen for days 1-25 and progestin for days 16-25, there is wide variation in prescribing strategies. We present these findings in the context of the probable effects of estrogen/progestin therapy on various chronic disease outcomes.
R K Ross; A Paganini-Hill; S Roy; A Chao; B E Henderson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of public health     Volume:  78     ISSN:  0090-0036     ISO Abbreviation:  Am J Public Health     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-05-12     Completed Date:  1988-05-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  1254074     Medline TA:  Am J Public Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  516-9     Citation Subset:  AIM; IM    
Department of Preventive Medicine, University of Southern California School of Medicine, Norris Cancer Hospital, Los Angeles 90033-0804.
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MeSH Terms
Climacteric / drug effects*
Drug Administration Schedule
Drug Therapy, Combination
Drug Utilization*
Estrogens / administration & dosage*
Middle Aged
Progestins / administration & dosage*
Grant Support
Reg. No./Substance:
0/Estrogens; 0/Progestins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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