Document Detail


Passive transfer of antibodies of maternal origin from blood to cerebrospinal fluid in infants.
MedLine Citation:
PMID:  47079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The demonstration that specific IgM antibodies are present in the serum of infants is useful in the diagnosis of several congenital infections. However, it is less certain whether the detection of antibodies in cerebrospinal fluid (c.s.f.) of infants indicates congenital infection of the central nervous system, because the origins of such antibodies have not been established. In the present study diphtheria and tetanus antitoxins of maternal origin have been detected both in the serum and in the c.s.f. of infants. These observations suggest that an important source of immunoglobulins in c.s.f. is passive transfer of antibodies from serum which should be considered in interpreting serological studies with c.s.f.
Authors:
J D Thorley; J M Kaplan; R K Holmes; G H McCracken; J P Sanford
Related Documents :
17564589 - Racial disparity in risk of preterm birth associated with lower genital tract infection.
18448489 - Serial viral infections in infants with recurrent respiratory illnesses.
2771529 - Failure of erythromycin ointment for postnatal ocular prophylaxis of chlamydial conjunc...
15244239 - Characteristics of respiratory syncytial virus-related apnoea in three infants.
9399489 - Molecular tracking of candida albicans in a neonatal intensive care unit: long-term col...
10213899 - Transmission of cervical cancer-associated human papilloma viruses from mother to child.
8982369 - Comparison of anastomotic suturing techniques in the rat trachea.
17466339 - Direct reciprocity on graphs.
20427879 - Congenital vitamin d deficiency: a rare etiology of an acute life threatening event in ...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Lancet     Volume:  1     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-06-02     Completed Date:  1975-06-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  651-3     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cerebrospinal Fluid / analysis*
Diphtheria / immunology
Diphtheria Antitoxin / isolation & purification*
Female
Hemagglutination Tests
Humans
Immunity, Maternally-Acquired*
Immunization, Passive
Immunoglobulin M / cerebrospinal fluid
Immunoglobulins / isolation & purification
Infant, Newborn
Maternal-Fetal Exchange*
Neurosyphilis / cerebrospinal fluid,  diagnosis,  immunology
Pregnancy
Syphilis Serodiagnosis
Tetanus / immunology
Tetanus Antitoxin / isolation & purification*
Chemical
Reg. No./Substance:
0/Diphtheria Antitoxin; 0/Immunoglobulin M; 0/Immunoglobulins; 0/Tetanus Antitoxin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hazards from simian herpes viruses: reactivation of skin lesions with virus shedding.
Next Document:  Refeeding-malaria and hyperferraemia.