Document Detail

Passage of stone fragments from the gallbladders of dogs.
MedLine Citation:
PMID:  2894076     Owner:  NLM     Status:  MEDLINE    
The destruction of gallstones by shock waves leads to a considerable amount of stone fragments in the gallbladder. To test the ability of the stones fragments to leave the gallbladder, kidney stone fragments of 2 or 4 millimeters maximal diameter were implanted into the gallbladders of 16 dogs and passage was observed for five weeks. Independent of stone size, about 35 per cent of the fragments remained in the gallbladder. Transient elevations of enzymes of the liver or pancreas occurred significantly less often with 2 millimeter fragments and were less pronounced. Gross pathologic changes of the papilla of Vater, or dilation of the bile duct were observed with 4 millimeter fragments but not with those that were 2 millimeters. The results of this study suggest that the maximal fragment size after destruction of gallstones should be as small as possible, that is, in the range of 2 millimeters.
M Delius; G Enders; W Brendel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Surgery, gynecology & obstetrics     Volume:  166     ISSN:  0039-6087     ISO Abbreviation:  Surg Gynecol Obstet     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-03-30     Completed Date:  1988-03-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0101370     Medline TA:  Surg Gynecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  241-4     Citation Subset:  AIM; IM    
Institute for Surgical Research, University of Munich, West Germany.
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MeSH Terms
Aspartate Aminotransferases / blood
Cholelithiasis / therapy*
Gallbladder / physiology*
L-Lactate Dehydrogenase / blood
Particle Size
alpha-Amylases / blood
gamma-Glutamyltransferase / blood
Reg. No./Substance:
EC Dehydrogenase; EC; EC Aminotransferases; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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