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Passage of radioactive erythrocytes from the peritoneal cavity into the blood stream during experimental ascites.
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MedLine Citation:
PMID:  15422086     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intraperitoneal injection of red cells tagged with radioiron into dogs with experimental ascites demonstrated that such cells were rapidly transferred into the circulating blood. When the experimental animals were not actively producing ascitic fluid, 43.4, 67.0, and 56.4 per cent respectively, of the administered radioactive red cells passed to the blood in 72 hours. In the same three dogs during active ascitic fluid formation, 25.9, 51.2, and 38.8 per cent of the administered radioactivity was removed in a similar period. The amount of radioactivity in the blood stream, consequent on the passage of red cells from the peritoneal cavity into the circulation, becomes nearly constant in 48 hours, whereas for radioactive plasma proteins the plateau is attained in 24 hours (Fig. 1). In normal dogs (16), the passage of red cells from the peritoneal cavity was complete in 72 hours, while in ascitic dogs, 5 to 47 per cent of the injected tagged red cells remained behind in the peritoneum after the same period.
Authors:
F W McKEE; W B STEWART
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  91     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1950 Jun 
Date Detail:
Created Date:  1950-12-01     Completed Date:  2004-09-30     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  599-605     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Ascites*
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Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1950, by The Rockefeller Institute for Medical Research New York
Received Day: 8 Month: 3 Year: 1950
Print publication date: Day: 1 Month: 6 Year: 1950
Volume: 91 Issue: 6
First Page: 599 Last Page: 605
ID: 2136013
PubMed Id: 15422086

PASSAGE OF RADIOACTIVE ERYTHROCYTES FROM THE PERITONEAL CAVITY INTO THE BLOOD STREAM DURING EXPERIMENTAL ASCITES
Frank W. McKee
Wellington B. Stewart
From the Department of Pathology, The University of Rochester, School of Medicine and Dentistry, Rochester, New York


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