Document Detail

Passage of food antigens into circulation of breast-fed infants with atopic dermatitis.
MedLine Citation:
PMID:  3189963     Owner:  NLM     Status:  MEDLINE    
We have selected 13 babies presenting with atopic dermatitis during exclusive breast feeding. After evaluation of reaginic reaction, we detected beta-lactoglobulin (BLG) in breast milk and babies sera before and after maternal elimination diet and after maternal challenge. beta-Lactoglobulin was present only in the sera of infants ingesting breast milk containing BLG. We have seen reaginic reactions to cow's milk in seven babies. The maternal elimination diet improved eczema in 11/13 infants, maternal challenge worsened atopic dermatitis in 9/9 children. We demonstrated the transport of food antigen via breast milk into infants' circulation.
G Cavagni; R Paganelli; C Caffarelli; G P D'Offizi; P Bertolini; F Aiuti; G Giovannelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of allergy     Volume:  61     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1988-12-08     Completed Date:  1988-12-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  361-5     Citation Subset:  IM    
Istituto di Clinica Pediatrica, dell'Universita' degli Studi di Parma, Italy.
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MeSH Terms
Breast Feeding*
Dermatitis, Atopic / etiology,  immunology*
Food Hypersensitivity / complications*
Immunoglobulin E / analysis
Lactoglobulins / analysis,  blood
Milk, Human / analysis
Radioallergosorbent Test
Skin Tests
Reg. No./Substance:
0/Lactoglobulins; 37341-29-0/Immunoglobulin E

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