| Passage of food antigens into circulation of breast-fed infants with atopic dermatitis. | |
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MedLine Citation:
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PMID: 3189963 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have selected 13 babies presenting with atopic dermatitis during exclusive breast feeding. After evaluation of reaginic reaction, we detected beta-lactoglobulin (BLG) in breast milk and babies sera before and after maternal elimination diet and after maternal challenge. beta-Lactoglobulin was present only in the sera of infants ingesting breast milk containing BLG. We have seen reaginic reactions to cow's milk in seven babies. The maternal elimination diet improved eczema in 11/13 infants, maternal challenge worsened atopic dermatitis in 9/9 children. We demonstrated the transport of food antigen via breast milk into infants' circulation. |
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Authors:
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G Cavagni; R Paganelli; C Caffarelli; G P D'Offizi; P Bertolini; F Aiuti; G Giovannelli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of allergy Volume: 61 ISSN: 0003-4738 ISO Abbreviation: Ann Allergy Publication Date: 1988 Nov |
Date Detail:
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Created Date: 1988-12-08 Completed Date: 1988-12-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372346 Medline TA: Ann Allergy Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 361-5 Citation Subset: IM |
Affiliation:
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Istituto di Clinica Pediatrica, dell'Universita' degli Studi di Parma, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Feeding* Dermatitis, Atopic / etiology, immunology* Female Food Hypersensitivity / complications* Humans Immunoglobulin E / analysis Infant Lactoglobulins / analysis, blood Male Milk, Human / analysis Radioallergosorbent Test Skin Tests |
| Chemical | |
Reg. No./Substance:
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0/Lactoglobulins; 37341-29-0/Immunoglobulin E |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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