Document Detail


Parvovirus-mediated fetal cardiomyopathy with atrioventricular nodal disease.
MedLine Citation:
PMID:  20936534     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Acute parvovirus B19 infection (API) in pregnancy has been associated with fetal anemia and hydrops fetalis. Direct myocardial damage from API in a fetus and an infant has been described. This report presents a case of fetal second-degree heart block and cardiomyopathy secondary to API. A 19-year-old G4P1112 (gravida 4 para 2 with 1 term delivery, 1 preterm delivery, 1 termination, and 2 living children) was referred at 20 weeks gestation for fetal bradycardia. A 2:1 atrioventricular block was identified by fetal echocardiography at 23 weeks. Hydrops developed at 25 weeks. Amniocentesis and percutaneous umbilical blood sampling demonstrated API. At 31 weeks, the patient presented with preterm labor and delivered a viable female infant, who died of poor cardiac function and arrhythmia on the first day of life. In addition to fetal anemia and hydrops fetalis, API in pregnancy may cause direct fetal myocardial damage and conduction system disease.
Authors:
Shira G Fishman; Linda M Pelaez; Rebecca N Baergen; Sheila J Carroll
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Publication Detail:
Type:  Journal Article     Date:  2010-10-12
Journal Detail:
Title:  Pediatric cardiology     Volume:  32     ISSN:  1432-1971     ISO Abbreviation:  Pediatr Cardiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-6     Citation Subset:  IM    
Affiliation:
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, 525 East 68th Street, Box 122, New York, NY 10065, USA. sgf2001@med.cornell.edu
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