Document Detail


Partitioning of persistent organic pollutants between blubber and blood of wild bottlenose dolphins: implications for biomonitoring and health.
MedLine Citation:
PMID:  20491435     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biomonitoring surveys of wild cetaceans commonly utilize blubber as a means to assess exposure to persistent organic pollutants (POPs), but the relationship between concentrations in blubber and those in blood, a better indicator of target organ exposure, is poorly understood. To define this relationship, matched blubber and plasma samples (n = 56) were collected from free-ranging bottlenose dolphins (Tursiops truncatus) and analyzed for 61 polychlorinated biphenyl (PCB) congeners, 5 polybrominated diphenyl ether (PBDE) congeners, and 13 organochlorine pesticides (OCPs). With the exception of PCB 209, lipid-normalized concentrations of the major POPs in blubber and plasma were positively and significantly correlated (R(2) = 0.828 to 0.976). Plasma concentrations, however, significantly increased with declining blubber lipid content, suggesting that as lipid is utilized, POPs are mobilized into blood. Compound- and homologue- specific blubber/blood partition coefficients also differed according to lipid content, suggesting POPs are selectively mobilized from blubber. Overall, these results suggest that with the regression parameters derived here, blubber may be used to estimate blood concentrations and vice versa. Additionally, the mobilization of lipid from blubber and concomitant increase in contaminants in blood suggests cetaceans with reduced blubber lipid may be at greater risk for contaminant-associated health effects.
Authors:
Jennifer E Yordy; Randall S Wells; Brian C Balmer; Lori H Schwacke; Teri K Rowles; John R Kucklick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Environmental science & technology     Volume:  44     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-11     Completed Date:  2010-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4789-95     Citation Subset:  IM    
Affiliation:
Hollings Marine Laboratory, National Institute of Standards and Technology, 331 Fort Johnson Road, Charleston, South Carolina 29412, USA. jennifer.yordy@noaa.gov
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MeSH Terms
Descriptor/Qualifier:
Animal Structures / metabolism*
Animals
Bottle-Nosed Dolphin / blood*
Environmental Monitoring*
Environmental Pollutants / blood*
Female
Health*
Lipids / analysis
Male
Organic Chemicals / blood*
Regression Analysis
Tissue Distribution
Chemical
Reg. No./Substance:
0/Environmental Pollutants; 0/Lipids; 0/Organic Chemicals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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