|Particularities of peripheral arterial disease managed in vascular surgery in the French West Indies.|
|PMID: 18391869 Owner: NLM Status: MEDLINE|
|BACKGROUND: Epidemiology of peripheral arterial disease is currently unknown in French West Indies (Antilles).
AIMS AND METHODS: The aim of this study is to present peripheral arterial disease (PAD) occurring in the French West Indian subjects through the analysis of our database of vascular surgery. The study population included 754 patients (mean age 73 +/- 10 years), mostly from African descents. The main clinical presentation was critical limb ischemia (66%, including tissue loss in 48% of cases), followed by claudication (20%). The lesions affected the infragenicular arteries in 86% of cases, including 24% isolated to this level as well as 51% combined to femoro-popliteal lesions and only 7% of cases affecting the aorto-iliac level.
RESULTS: Ankle-brachial index was at 0.57 +/- 0.13 and 0.34 +/- 0.22 (p<0.001) in patients with claudication and critical limb ischemia (CLI), respectively. The severity scores were significantly higher in claudicants with aorto-iliac disease and CLI patients with infragenicular lesions. Except for hypertension (85%) and obesity (19%), the other risk factors were differently distributed between the 2 groups. While in the CLI group, patients were older, with higher rates of female sex, diabetes (62% vs. 48%, p<0.001) and severe renal failure, claudicants were significantly younger, with higher rates of smokers among men (75% vs. 51%, p<0.001) and moderate dyslipidemia (52% vs. 36%, p<0.001). The association with carotid stenosis (12%) and ischemic heart disease (18%) were quite uncommon. Renal disease (glomerular filtration rate<60 ml/mn/1.73 m2) was present in 61% of cases.
CONCLUSION: This study highlights clear differences regarding the presentation, localization and associations of PAD in the West Indies subjects managed in vascular surgery, especially with a severe infragenicular disease, even in claudicants. This study suggests the effect of a different distribution of risk factors as well as other ethnic and socio-economic factors.
|M Deneuville; J M Pierrot; R N'guyen|
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|Type: Journal Article|
|Title: Archives of cardiovascular diseases Volume: 101 ISSN: 1875-2136 ISO Abbreviation: Arch Cardiovasc Dis Publication Date: 2008 Jan|
|Created Date: 2008-04-08 Completed Date: 2008-05-29 Revised Date: 2011-04-25|
Medline Journal Info:
|Nlm Unique ID: 101465655 Medline TA: Arch Cardiovasc Dis Country: Netherlands|
|Languages: eng Pagination: 23-9 Citation Subset: IM|
|Service de chirurgie vasculaire et thoracique, CHU de Pointe-à-Pitre-Abymes, France. firstname.lastname@example.org|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Ankle / blood supply
Aortic Diseases / complications, epidemiology, etiology, physiopathology, surgery*
Brachial Artery / physiopathology
Extremities / blood supply*
Femoral Artery / surgery
Guadeloupe / epidemiology
Iliac Artery / surgery
Intermittent Claudication / epidemiology, etiology*, physiopathology, surgery
Ischemia / epidemiology, etiology*, physiopathology, surgery
Peripheral Vascular Diseases / complications, epidemiology, etiology, physiopathology, surgery*
Popliteal Artery / surgery
Severity of Illness Index
Vascular Surgical Procedures* / statistics & numerical data
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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