Document Detail


Particular significance of SRD2-dependent snRNA accumulation in polarized pattern generation during lateral root development of Arabidopsis.
MedLine Citation:
PMID:  20965997     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Lateral root primordia are initiated by anticlinal division of cells in the pericycle and are constructed through an ordered set of cell divisions. At the completion of the development of the primordium, cell division ceases, after which the lateral root meristem is activated. In Arabidopsis, this course of lateral root morphogenesis was found to be significantly susceptible to srd2-1, a temperature-sensitive mutation of the SRD2 gene encoding an activator of small nuclear RNA (snRNA) transcription. The srd2-1 mutation altered the organization of cells of the root primordium and, importantly, maintained primordial cell division for a long period, resulting in the formation of abnormal hemispherical laterals. Expression patterns of various reporter genes suggested that both the apical-basal and radial axes were not well established in the lateral root primordia of the srd2-1 mutant. In the early stages of development of the primordium, the srd2-1 mutation reduced the amount of the auxin efflux facilitator PIN-FORMED (PIN) and, probably by this means, interfered with the generation of an auxin gradient. Spliceosomal snRNAs accumulated at high levels throughout young root primordia and then decreased in association with the arrest of cell division, and finally increased again when the apical meristem became activated. The accumulation of snRNAs was severely suppressed by the srd2-1 mutation, and this was detectable before any morphological defect became evident. These findings suggest that high-level accumulation of snRNA involving the SRD2 function is particularly important for expression of PINs in polarized pattern generation during the development of lateral root primordia.
Authors:
Misato Ohtani; Taku Demura; Munetaka Sugiyama
Related Documents :
11250167 - Cell polarity: squaring the circle.
16303827 - Microtubule arrays and arabidopsis stomatal development.
9725857 - Arabidopsis tso1 regulates directional processes in cells during floral organogenesis.
15261157 - Cell division induced by mechanical stimulation in starved tetrahymena thermophila: cel...
22494057 - Dimethylsulfoxide exposure modulates hl-60 cell rolling interactions.
7615447 - Leukotriene b4 formation: human neutrophil-airway epithelial cell interactions.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-10-21
Journal Detail:
Title:  Plant & cell physiology     Volume:  51     ISSN:  1471-9053     ISO Abbreviation:  Plant Cell Physiol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430925     Medline TA:  Plant Cell Physiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2002-12     Citation Subset:  IM    
Affiliation:
Biomass Engineering Program, RIKEN, Yokohama, 230-0045 Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Sudden coronary death-not always atherosclerotic.
Next Document:  Mitogen-activated protein kinase regulated by the CLAVATA receptors contributes to shoot apical meri...