| Particle motion is broadly represented in the vestibular medulla of the bullfrog across larval development. | |
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MedLine Citation:
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PMID: 22198742 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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In their shallow-water habitats, bullfrog (Rana catesbeiana) tadpoles are exposed to both underwater and airborne sources of acoustic stimulation. We probed the representation of underwater particle motion throughout the tadpole's dorsal medulla to determine its spatial extent over larval life. Using neurobiotin-filled micropipettes, we recorded neural activity to z-axis particle motion (frequencies of 40-200 Hz) in the medial vestibular nucleus, lateral vestibular nucleus, dorsal medullary nucleus (DMN), and along the dorsal arcuate pathway. Sensitivity was comparable in the medial and lateral vestibular nuclei, with estimated thresholds between 0.016 and 12.5 μm displacement. Neither best responding frequency nor estimated threshold varied significantly over larval stage. Transport of neurobiotin from active recording sites was also stable over development. The DMN responded poorly to z-axis particle motion, but did respond to low-frequency pressure stimulation. These data suggest that particle motion is represented widely and stably in the tadpole's vestibular medulla. This is in marked contrast to the representation of pressure stimulation in the auditory midbrain, where a transient "deaf period" of non-responsiveness and decreased connectivity occurs immediately prior to metamorphic climax. We suggest that, in bullfrogs, sensitivity to particle motion and to pressure follows different developmental trajectories. |
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Authors:
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Andrea Megela Simmons; Victoria Flores |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-24 |
Journal Detail:
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Title: Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology Volume: - ISSN: 1432-1351 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101141792 Medline TA: J Comp Physiol A Neuroethol Sens Neural Behav Physiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Cognitive, Linguistic and Psychological Sciences, Brown University, Box 1821, Providence, RI, 02912, USA, Andrea_Simmons@brown.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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