| Participation in an ambulatory e-pharmacovigilance system. | |
| | |
MedLine Citation:
|
PMID: 20623512 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: There is growing concern about whether passive surveillance can detect adverse drug events (ADEs). Our objective was to demonstrate the reach of an interactive voice response system (IVRS) to systematically monitor symptoms experienced by ambulatory patients prescribed one of 31 medications, and to document whether there were differences in our ability to contact certain populations. METHODS: Patients receiving a prescription for a target medication at one of 11 clinics were eligible for a cross-sectional IVRS survey, "e-pharmacovigilance," with a follow-up survey done 3 months later if the target medication was still listed on the patient's active medication list. RESULTS: 902 patients participated, representing 43.3% of contacted and 25.7% of potentially eligible patients with a working phone. After adjustment for demographics and drug class, patients >66 years were more likely to participate than those 56-65 years (odds ratio 1.47; 95% confidence interval 1.19-1.81). Hispanics were less likely than whites (0.56; 0.42-0.76), and those in low-income communities less likely to participate than those in high-income communities (0.69; 0.58-0.82). Patients prescribed asthma, or seizure medications were more likely to participate than those prescribed medications for insomnia. Of patients reached by the system, those prescribed medications were erectile dysfunction and smoking cessation were less likely, and those prescribed seizure medication were more likely to participate. CONCLUSIONS: IVRS technology can be used to perform ambulatory e-pharmacovigilance for a broad spectrum of patients, particularly older individuals who may at particular risk for ADEs. |
| | |
Authors:
|
Jennifer S Haas; Aarthi Iyer; E John Orav; Gordon D Schiff; David W Bates |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Pharmacoepidemiology and drug safety Volume: 19 ISSN: 1099-1557 ISO Abbreviation: Pharmacoepidemiol Drug Saf Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-02 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9208369 Medline TA: Pharmacoepidemiol Drug Saf Country: England |
Other Details:
|
Languages: eng Pagination: 961-9 Citation Subset: IM |
Copyright Information:
|
Copyright (c) 2010 John Wiley & Sons, Ltd. |
Affiliation:
|
Division of General Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA 02120, USA. jhaas@partners.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Adverse Drug Reaction Reporting Systems* Age Factors Aged Ambulatory Care / methods Cross-Sectional Studies Data Collection Female Follow-Up Studies Hispanic Americans Humans Male Middle Aged Patient Acceptance of Health Care Prescription Drugs / adverse effects* Socioeconomic Factors Speech Recognition Software Telephone* Young Adult |
| Grant Support | |
ID/Acronym/Agency:
|
U18HS016970/HS/AHRQ HHS |
| Chemical | |
Reg. No./Substance:
|
0/Prescription Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Physiological effects of resveratrol.
Next Document: Adverse drug events in the outpatient setting: an 11-year national analysis.