Document Detail


Partially inverted tandem repeat isolated from pericentric region of chicken chromosome 8.
MedLine Citation:
PMID:  11863074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The majority of chicken repetitive sequence is nuclear-membrane-associated sequence (CNM), which resides in a large number of microchromosomes (chromosomes 11-39) and is absent from macrochromosomes 1-5, ZW, and some of the intermediate chromosomes 6-10. Two repetitive families, EcoRI/XhoI, are confined to the female-specific W chromosome. The core repeat units of the three families are 21 bp, containing (A)3-5 and (T)3-5 clusters separated by 5-7-bp sequences. In this article, we describe the isolation and initial characterization of a novel repeat family that is related to CNM/EcoRI/XhoI families. The novel family, designated as PIR, consists of multiple types of partially inverted repeat units of about 1.2, 1.4 and 1.6 kb. The PIR sequence is restricted to chicken chromosome 8, and accounts for about 3.8 mb, or 2500 copies of the 1.4-kb units, of the chicken genome. The evolution of PIR and related sequences is discussed.
Authors:
Xiaofei Wang; Juan Li; Frederick C Leung
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology     Volume:  10     ISSN:  0967-3849     ISO Abbreviation:  Chromosome Res.     Publication Date:  2002  
Date Detail:
Created Date:  2002-02-26     Completed Date:  2002-08-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9313452     Medline TA:  Chromosome Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  73-82     Citation Subset:  IM    
Affiliation:
Department of Zoology, The University of Hong Kong, SAR, China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Base Sequence
Chickens / genetics*
Chromosome Mapping*
DNA Primers
In Situ Hybridization, Fluorescence
Molecular Sequence Data
Polymerase Chain Reaction
Repetitive Sequences, Nucleic Acid
Restriction Mapping
Chemical
Reg. No./Substance:
0/DNA Primers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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