| Partial status epilepticus induced by hypocupremia in a patient with Wilson's disease. | |
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MedLine Citation:
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PMID: 20732822 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although seizures are rarely encountered in Wilson's disease (WD), seizures related to hypocupremia have not been reported before. We report a patient presenting with partial status epilepticus who was on strict low-copper diet and chelating therapy for WD. Despite other rare causes of seizures in WD including penicillamine-induced pyridoxine deficiency, cerebral copper deposition and metabolic encephalopathy, the most probable cause of resistant status epilepticus in this patient was found as hypocupremia from overzealous treatment. This case exemplifies that hypocupremic states should be kept in mind as a risk factor for resistant seizures. |
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Authors:
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Gulcin Benbir; Aysegul Gunduz; Sibel Ertan; Cigdem Ozkara |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-08-22 |
Journal Detail:
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Title: Seizure : the journal of the British Epilepsy Association Volume: 19 ISSN: 1532-2688 ISO Abbreviation: Seizure Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-18 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9306979 Medline TA: Seizure Country: England |
Other Details:
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Languages: eng Pagination: 602-4 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Cerrahpasa Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Turkey. drgulcinbenbir@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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pathology,
physiopathology Copper / blood, deficiency* Electroencephalography Epilepsies, Partial / blood, etiology*, physiopathology Hepatolenticular Degeneration / blood, complications*, drug therapy Humans Magnetic Resonance Imaging Male Penicillamine / adverse effects, therapeutic use Young Adult |
| Chemical | |
Reg. No./Substance:
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52-67-5/Penicillamine; 7440-50-8/Copper |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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