Document Detail


Partial splenic artery embolization for thrombocytopenia and uncontrolled massive ascites after liver transplantation.
MedLine Citation:
PMID:  22483487     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Thrombocytopenia (platelet < 60,000/mm(3)) and uncontrolled massive ascites (ascitic fluid > 1000 mL/d over 10 days) after liver transplantation (OLT), although uncommon, usually represent serious complications. Splenectomy is a useful treatment despite its many side effects. Recently, partial splenic artery embolization (PSAE) is considered to be a nonsurgical, less invasive treatment. In this study, we retrospectively reviewed the results of PSAE after OLT. Between October 2008 and February 2010, 11 patients underwent PSAE after OLT due to thrombocytopenia (n = 6) or refractory ascites (RA; n = 5). Six patients (54.5%) were males and 3 (27.3%) were children. The primary liver disease was virus-related liver cirrhosis (n = 6), biliary atresia (n = 3), fulminant hepatitis (n = 1), or alcoholic liver cirrhosis (n = 1). Seven grafts were from living and four from deceased donors. The major axial size of spleen was 12.1 to 23.4 cm and its average embolized volume, 76.4% (range = 70%-80%). As the result, the platelet count significantly increased after PSAE in all patients maintaining values greater than 100,000/mm(3) in four thrombocytopenic patients (66.7%). Cases of RA showed marked decreases after PSAE (100%). The follow-up was 6 to 28 months. After PSAE, patients experienced abdominal pain (n = 9, 81.8%), fever (n = 2, 18.2%), and abdominal distension (n = 2, 18.2%). However, there was no serious complication after PSAE such as splenic abscess, rupture, pancreatic infarction, sepsis, or death. In conclusion, PSAE was effective and safe and can be the choice for thrombocytopenia or RA related to hypersplenism after OLT.
Authors:
H Kim; K S Suh; Y M Jeon; M S Park; Y Choi; S Mori; G Hong; H W Lee; N J Yi; K W Lee
Related Documents :
19940787 - Is the inverse relation between blood pressure and mortality normalized in 'low-risk' d...
10982047 - Necrotising enterocolitis (nec)--methods of treatment and outcome: a comparative analys...
20639677 - Outcome of hemodialysis patients who had failed peritoneal dialysis.
2373667 - Oral pefloxacin mesylate in the treatment of continuous ambulatory peritoneal dialysis ...
23232827 - Is it really necessary to delay intranasal steroid treatment after fess? an animal study.
17643497 - Sporadic acoustic neuroma in pediatric patients.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  44     ISSN:  1873-2623     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  755-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Predictive factors for persistent splenomegaly and hypersplenism after adult living donor liver tran...
Next Document:  Effect of pulmonary support using extracorporeal membrane oxygenation for adult liver transplant rec...