Document Detail


Partial monosomy of distal 10q: three new cases and a review.
MedLine Citation:
PMID:  10440820     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on 3 patients with partial deletions of the long arm of chromosome 10-46,XY,del (10)(q26.2), 46,XX,del(10) (q25.3q26.3) or 46,XX,del(10)(q26.1), and 46,XX,del (10)(q26.1). They are compared with other known cases with interstitial or terminal deletions involving chromosome bands 10q25 or q26. Unique manifestations are identified, including scoliosis and a severe behavior disorder with attention deficit and hyperactivity in a 12-year-old boy as well as patchy alopecia in a 6-year-old patient.
Authors:
D J Waggoner; C K Chow; S B Dowton; M S Watson
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of medical genetics     Volume:  86     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-09-10     Completed Date:  1999-09-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
Copyright Information:
Copyright 1999 Wiley-Liss, Inc.
Affiliation:
Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics
Child
Chromosome Breakage / genetics
Chromosome Deletion*
Chromosomes, Human, Pair 10 / genetics*
Female
Heart Diseases / congenital,  genetics
Humans
Male
Monosomy / genetics*
Phenotype
Sex Differentiation / genetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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