Document Detail


Partial genetic turnover in neandertals: continuity in the east and population replacement in the west.
MedLine Citation:
PMID:  22362080     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Remarkably little is known about the population-level processes leading up to the extinction of the neandertal. To examine this, we use mtDNA sequences from 13 neandertal individuals, including a novel sequence from northern Spain, to examine neandertal demographic history. Our analyses indicate that recent western European neandertals (<48 kyr) constitute a tightly defined group with low mitochondrial genetic variation in comparison to both eastern and older (>48 kyr) European neandertals. Using control region sequences, Bayesian demographic simulations provide higher support for a model of population fragmentation followed by separate demographic trajectories in subpopulations over a null model of a single stable population. The most parsimonious explanation for these results is that of a population turnover in western Europe during early Marine Isotope Stage 3, predating the arrival of anatomically modern humans in the region.
Authors:
Love Dalén; Ludovic Orlando; Beth Shapiro; Mikael Brandström Durling; Rolf Quam; M Thomas P Gilbert; J Carlos Díez Fernández-Lomana; Eske Willerslev; Juan Luis Arsuaga; Anders Götherström
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-23
Journal Detail:
Title:  Molecular biology and evolution     Volume:  -     ISSN:  1537-1719     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501455     Medline TA:  Mol Biol Evol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Molecular Systematics, Swedish Museum of Natural History, Box 50007, 104 05 Stockholm, Sweden.
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