| Partial food restriction increases hepatic inner ring deiodinating activity in the chicken and the rat. | |
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MedLine Citation:
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PMID: 8775060 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of a long term partial food restriction were studied in chickens and rats. In chickens the treatment resulted in increased plasma T4 levels while T4 levels in rats remained unchanged. Plasma T3 decreased in both species. In vitro hepatic outer ring deiodinating type I (ORD-I) activity was not influenced by the food restriction, suggesting that the amount of ORD-I enzyme present in the liver remained unchanged. In vitro hepatic inner ring deiodinating type III activity, on the contrary, was greatly increased in both species. This increase may contribute to the decreased circulating T3 levels by increasing the degradation of T3 and diverting the deiodination of T4 to rT3 instead of to T3. |
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Authors:
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V M Darras; M Cokelaere; E Dewil; S Arnouts; E Decuypere; E R Kühn |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: General and comparative endocrinology Volume: 100 ISSN: 0016-6480 ISO Abbreviation: Gen. Comp. Endocrinol. Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-12-03 Completed Date: 1996-12-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370735 Medline TA: Gen Comp Endocrinol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 334-8 Citation Subset: IM |
Affiliation:
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Laboratory of Comparative Endocrinology, Zoological Institute, KULeuven, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Weight Chickens Diet / adverse effects* Female Liver / metabolism* Male Rats Rats, Wistar Thyroid Hormones / blood* |
| Chemical | |
Reg. No./Substance:
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0/Thyroid Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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