Document Detail

Partial and complete expulsion of the Multiload 375 IUD and the levonorgestrel-releasing IUD after correct insertion.
MedLine Citation:
PMID:  17353086     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The contraceptive efficacy of intrauterine devices (IUD) is thought to relate to the position of the IUD in the uterine cavity. Several trials examined the number of copper IUD expulsions, but none evaluated the partial and complete expulsion rate of the levonorgestrel-releasing device (LNG-IUD). STUDY DESIGN: This retrospective cohort study compares the dislocation rate of the Multiload 375 IUD (ML 375) and the LNG-IUD in 214 women (107 subjects with each IUD). Transvaginal ultrasound was used to monitor the IUD position immediately after insertion, after 6 weeks, and later on at intervals of 6 months. The observation period included 3631 cycles. RESULTS: We detected a significantly lower number of dislocations in LNG-IUD users. Previous expulsion was associated with a significantly higher risk for a re-expulsion in both IUD groups. Hypermenorrhea was not associated with an increased dislocation rate in LNG-IUD users. CONCLUSION: Expulsions are less likely to occur with the LNG-IUD, which might contribute to its contraceptive efficacy.
Gabriele S Merki-Feld; Danielle Schwarz; B Imthurn; P J Keller
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-03-13
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  137     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-25     Completed Date:  2008-06-17     Revised Date:  2009-05-07    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  92-6     Citation Subset:  IM    
Clinic of Endocrinology, Department of Gynecology and Obstetrics, University Hospital, Frauenklinikstr. 10, CH-8091 Zurich, Switzerland.
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MeSH Terms
Cohort Studies
Contraceptive Agents, Female / administration & dosage*
Copper / administration & dosage*
Intrauterine Device Expulsion* / etiology
Intrauterine Devices* / adverse effects
Levonorgestrel / administration & dosage*
Retrospective Studies
Risk Factors
Uterine Contraction
Uterus / ultrasonography
Reg. No./Substance:
0/Contraceptive Agents, Female; 7440-50-8/Copper; 797-63-7/Levonorgestrel
Comment In:
Eur J Obstet Gynecol Reprod Biol. 2009 Mar;143(1):64; author reply 64-5   [PMID:  19150168 ]
Erratum In:
Eur J Obstet Gynecol Reprod Biol. 2009 Mar;143(1):66

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