Document Detail

Partial replacement of tricuspid valve using cryopreserved homograft.
MedLine Citation:
PMID:  20338330     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The optimal choice of prosthesis for tricuspid valve (TV) replacement is yet to be determined. Partial replacement of the TV using a homograft atrioventricular valve might offer resistance to infection, good durability, and excellent functionality, in addition to avoiding prosthesis-related morbidity.
METHODS: We present 14 patients who underwent replacement of the TV using a homograft between 1997 and 2008. The mean age at operation was 32 years, including 5 patients younger than the age of 10. All patients preoperatively showed severe TV regurgitation as a result of active infective endocarditis in 5 patients, Ebstein anomaly in 4 patients, other cardiac anomalies in 4 patients, and rheumatic valvular disease in 1 patient. The TV homograft was used in 13 patients, and mitral homograft was used in 1 patient. Eleven patients had replacement of one leaflet only, whereas 3 patients required replacement of two leaflets. Concomitant cardiac procedures were performed in 7 patients.
RESULTS: No mortalities occurred during the average postoperative follow-up of 61 months (range, 12 to 126 months). Reoperation for TV regurgitation after TV repair with homograft was performed in 3 patients. The remaining 11 patients had minimal symptoms without reintervention for TV regurgitation.
CONCLUSIONS: Partial replacement of the TV using a homograft provided good hospital and mid-term outcomes. This strategy might be useful in active infective endocarditis and congenital TV disease.
Bishwo M S Shrestha; Satsuki Fukushima; Marian Vrtik; Ian H Chong; Lisa Sparks; Homayoun Jalali; Peter G Pohlner
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  89     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-26     Completed Date:  2010-04-26     Revised Date:  2011-02-14    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1187-94     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Division of Cardiothoracic Surgery, The Prince Charles Hospital, Brisbane, Australia.
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MeSH Terms
Cardiac Surgical Procedures / methods
Infant, Newborn
Middle Aged
Mitral Valve / surgery,  transplantation*
Mitral Valve Insufficiency / surgery*
Time Factors
Treatment Outcome
Tricuspid Valve / surgery,  transplantation*
Tricuspid Valve Insufficiency / surgery*
Young Adult
Comment In:
Ann Thorac Surg. 2010 Apr;89(4):1194   [PMID:  20338331 ]
Ann Thorac Surg. 2011 Feb;91(2):645-6; author reply 646   [PMID:  21256351 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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