Document Detail


Paroxysmal nocturnal dystonia presenting as excessive daytime somnolence.
MedLine Citation:
PMID:  2106869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the clinical and electrophysiologic findings in seven patients referred for evaluation of excessive daytime somnolence. These patients had none of the usual causes of excessive daytime somnolence but during sleep exhibited stereotypic body movements, tachycardia, respiratory disturbances, somniloquy, and transient arousals in a repetitive fashion. These episodes induced fragmentation of sleep. The polysomnograms revealed an increase in wakefulness and stage I decreased rapid eye movement during sleep in addition to the episodes of abnormal body movements. No epileptiform features were present either in the electroencephalogram or in the nocturnal polysomnogram. Four of the seven patients were treated with anticonvulsants, with both subjective and objective improvement on subsequent follow-up polysomnograms. Because of the pronounced functional deficits associated with the sleep disorder in these patients, it is of great importance to recognize the disorder and treat it appropriately.
Authors:
M Maccario; L I Lustman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  47     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-03-30     Completed Date:  1990-03-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco, Calif. 94129-6700.
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MeSH Terms
Descriptor/Qualifier:
Adult
Carbamazepine / therapeutic use
Diagnosis, Differential
Dystonia / diagnosis*,  drug therapy
Electroencephalography
Evaluation Studies as Topic
Female
Humans
Imipramine / therapeutic use
Male
Middle Aged
Phenobarbital / therapeutic use
Sleep Disorders / diagnosis*,  drug therapy
Sleep Stages / physiology*
Trifluoperazine / therapeutic use
Valproic Acid / therapeutic use
Chemical
Reg. No./Substance:
117-89-5/Trifluoperazine; 298-46-4/Carbamazepine; 50-06-6/Phenobarbital; 50-49-7/Imipramine; 99-66-1/Valproic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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