Document Detail

Paroxysmal episodic hypothalamic instability with hypothermia after traumatic brain injury.
MedLine Citation:
PMID:  16286344     Owner:  NLM     Status:  MEDLINE    
This case report describes a patient in vegetative state after severe traumatic brain injury (TBI) with hypothalamic damage and clinical manifestations of autonomic dysfunction. He also presented late onset paroxysmal hypothermia associated with mild bradycardia and hypotension. Hypothermia due to traumatic lesions of the hypothalamus is an uncommon clinical problem and few cases have been reported; no cases could be found in the literature which evidenced periodic hypothermia associated with clinical features of autonomic dysfunction after TBI. In the article, the main causes and the primary pathophysiology of hypothermia after TBI are discussed. The manifestations in this patient have been interpreted as possible consequences of autonomic dysfunction and considered atypical and rare clinical expression of acute post-traumatic hypothalamic instability.
Antonio De Tanti; Giulio Gasperini; Mauro Rossini
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Brain injury     Volume:  19     ISSN:  0269-9052     ISO Abbreviation:  Brain Inj     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-11-15     Completed Date:  2006-02-21     Revised Date:  2014-11-14    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  England    
Other Details:
Languages:  eng     Pagination:  1277-83     Citation Subset:  IM    
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MeSH Terms
Accidents, Traffic
Brain Injuries / complications*
Fever / etiology
Hypothalamus / injuries*,  physiopathology
Hypothermia / etiology*
Persistent Vegetative State / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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