Document Detail

Paroxysmal atrial fibrillation is uncommon in outpatients with chronic heart failure.
MedLine Citation:
PMID:  18569952     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The objective was to evaluate the prevalence of paroxysmal atrial fibrillation (PAF) in patients with heart failure (HF) due to systolic dysfunction. DESIGN: We included 79 patients (age 68 years, LVEF 30%) with HF and sinus-rhythm (SR) referred to a HF outpatient clinic. A 48 hours Holter ECG and a follow-up ECG were performed. RESULTS. One patient had one episode of PAF. Thirty-two (41%) patients had episodes of irregular atrial runs (AR). The numbers of QRS complexes during AR were 7.2+/-2.9 (mean+/-SD). Patients with AR were older than patients with SR, p =0.02 and more often of female sex, p =0.04. Multivariate logistic regression analysis showed that age and female sex were independently correlated with AR with adjusted OR of 1.1 (per year, 95% CI 1.02-1.14, p =0.01) and 4.0 (1.05-15.07, p =0.04), respectively. The presence of AR did not predict development of new-onset AF. CONCLUSION: Outpatients with HF due to systolic dysfunction did not present with PAF during 48 hours Holter, but had several episodes of AR. The clinical and prognostic importance of AR deserves further investigation.
Pernille Corell; Finn Gustafsson; Jesper Mehlsen; Jens Rosenberg; Per Hildebrandt
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian cardiovascular journal : SCJ     Volume:  42     ISSN:  1401-7431     ISO Abbreviation:  Scand. Cardiovasc. J.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-10-10     Revised Date:  2009-02-05    
Medline Journal Info:
Nlm Unique ID:  9708377     Medline TA:  Scand Cardiovasc J     Country:  England    
Other Details:
Languages:  eng     Pagination:  202-7     Citation Subset:  IM    
Department of Cardiology and Endocrinology, Frederiksberg University Hospital, Frederiksberg, Denmark.
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MeSH Terms
Age Factors
Atrial Fibrillation / epidemiology*,  etiology,  physiopathology
Chronic Disease
Denmark / epidemiology
Electrocardiography, Ambulatory
Heart Failure, Systolic / complications,  epidemiology*,  physiopathology
Logistic Models
Middle Aged
Odds Ratio
Outpatients / statistics & numerical data*
Risk Assessment
Risk Factors
Sex Factors
Comment In:
Scand Cardiovasc J. 2008 Dec;42(6):366; author reply 367   [PMID:  18932093 ]

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