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Parotid Gland Metastasis of Breast Cancer: Case Report and Review of the Literature.
MedLine Citation:
PMID:  22419903     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Parotid gland metastasis in breast cancer is extremely rare, and only 14 cases have been reported between 1982 and 2010. CASE REPORT: A 67-year-old female patient was diagnosed with invasive lobular carcinoma of the left breast. Although clinical staging was T1N3M1 (stage IV), the tumor experienced a complete response to chemotherapy. We therefore performed a mastectomy followed by radiotherapy, and continued administration of trastuzumab. However, 11 months later, the patient complained of a swelling in the left parotid gland. Histology following a partial parotidectomy revealed a parotid gland metastasis from the breast. CONCLUSION: Treatment with capecitabine in addition to trastuzumab, which is one of the strategies applied in HER2-positive breast cancer, was effective in our patient. Analysis of the 14 cases of parotid gland metastasis from the breast reported between 1982 and 2010 revealed that the metastasis may occur not by direct lymphatic but by hematogenous spread.
Authors:
Katsutoshi Ando; Norio Masumoto; Masaaki Sakamoto; Kou Teraoka; Takako Suzuki; Terumasa Kurihara; Satoko Abe; Mitsuhiro Tozaki; Eisuke Fukuma; Kazuei Hoshi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-20
Journal Detail:
Title:  Breast care (Basel, Switzerland)     Volume:  6     ISSN:  1661-3805     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-3-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101254060     Medline TA:  Breast Care (Basel)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  471-473     Citation Subset:  -    
Affiliation:
Breast Center, Kamogawa, Chiba, Japan.
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