Document Detail


Parnapimarol and nepetaparnone from Nepeta parnassica.
MedLine Citation:
PMID:  18393463     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Parnapimarol (1), a new pimarane diterpene, along with nepetaparnone (2) and nepetanudone (3), one new and one previously reported nepetalactone dimer, respectively, were isolated from the dichloromethane extract of the aerial parts of Nepeta parnassica, collected on Mt. Parnassos, Greece. The structures and relative configurations of 1-3 were determined on the basis of their spectroscopic characteristics (1D and 2D NMR, IR, MS). The structure of 2 was confirmed by single-crystal X-ray diffraction analysis. The insecticidal activity of 1-3 against ants and mosquito larvae was also evaluated.
Authors:
Giorgos Gkinis; Efstathia Ioannou; Antonio Quesada; Constantinos Vagias; Olga Tzakou; Vassilios Roussis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-04-05
Journal Detail:
Title:  Journal of natural products     Volume:  71     ISSN:  0163-3864     ISO Abbreviation:  J. Nat. Prod.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-23     Completed Date:  2008-07-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906882     Medline TA:  J Nat Prod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  926-8     Citation Subset:  IM    
Affiliation:
Department of Pharmacognosy and Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, Greece.
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MeSH Terms
Descriptor/Qualifier:
Animals
Ants / drug effects
Crystallography, X-Ray
Culicidae / drug effects
Diterpenes, Abietane / chemistry,  isolation & purification*,  pharmacology
Greece
Insecticides / chemistry,  isolation & purification*,  pharmacology
Lactones / chemistry,  isolation & purification*,  pharmacology
Larva / drug effects
Molecular Conformation
Molecular Structure
Nepeta / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Plants, Medicinal / chemistry*
Chemical
Reg. No./Substance:
0/Diterpenes, Abietane; 0/Insecticides; 0/Lactones; 0/nepetanudone; 0/nepetaparnone; 0/parnapimarol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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