Document Detail

Parkinsonism and midbrain dysfunction after shunt placement for obstructive hydrocephalus.
MedLine Citation:
PMID:  16542840     Owner:  NLM     Status:  MEDLINE    
We report a patient in whom placement of a ventriculoperitoneal shunt for obstructive hydrocephalus secondary to non-neoplastic aqueductal stenosis was complicated by progressive parkinsonism and midbrain dysfunction. These sequelae were refractory to treatment, including shunt revision and levodopa therapy. These findings contradict the opinion from the literature that this type of parkinsonism is a reversible condition and levodopa therapy is effective for managing the symptoms. We discuss the pathophysiological mechanism of this complication.
Shoji Yomo; Kazuhiro Hongo; Takayuki Kuroyanagi; Shigeaki Kobayashi
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-03-20
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  13     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-07-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  373-8     Citation Subset:  IM    
Department of Neurosurgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.
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MeSH Terms
Hydrocephalus / surgery*
Magnetic Resonance Imaging / methods
Mesencephalon / pathology*
Middle Aged
Parkinson Disease / etiology*
Time Factors
Ventriculoperitoneal Shunt / adverse effects*

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