Document Detail

Parkinsonism in a patient with antiphospholipid syndrome--case report and literature review.
MedLine Citation:
PMID:  17996905     Owner:  NLM     Status:  MEDLINE    
Antiphospholipid syndrome (APS) is identified as the presence of antiphospholipid antibodies (aPLs) in patients with vascular thrombosis and/or pregnancy morbidity (including fetal death, premature birth and habitual abortion). Neurological manifestations in patients with APS are common, whereas movement disorders are rarely seen. We report an extremely rare case of APS presented with parkinsonism and review the literature to address the clinical profile and possible pathophysiologic mechanism of this disorder.
Yen-Chu Huang; Rong-Kuo Lyu; Sien-Tsong Chen; Yi-Chuan Chu; Yih-Ru Wu
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-11-09
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  267     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-02-22     Completed Date:  2008-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  166-9     Citation Subset:  IM    
Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine 199 Tung Hwa North Road, Taipei, 10591, Taiwan.
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MeSH Terms
Anticoagulants / therapeutic use
Antiparkinson Agents / therapeutic use
Antiphospholipid Syndrome / complications*
Brain / blood supply,  pathology*,  physiopathology
Cerebral Arteries / pathology,  physiopathology
Corpus Striatum / metabolism,  physiopathology,  radionuclide imaging
Dementia, Vascular / etiology,  pathology,  physiopathology
Intracranial Thrombosis / etiology*,  pathology*,  physiopathology
Levodopa / therapeutic use
Magnetic Resonance Imaging
Middle Aged
Neuropsychological Tests
Parkinsonian Disorders / etiology*,  pathology*,  physiopathology
Tomography, Emission-Computed, Single-Photon
Treatment Outcome
Warfarin / therapeutic use
Reg. No./Substance:
0/Anticoagulants; 0/Antiparkinson Agents; 0/Levodopa; 81-81-2/Warfarin

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