Document Detail

Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate).
MedLine Citation:
PMID:  7801076     Owner:  NLM     Status:  MEDLINE    
Permanent parkinsonism was observed in a man with chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Symptoms developed at 37 years of age, two years after exposure had ceased. To our knowledge, this is the second report on parkinsonism associated with exposure to maneb. Manganese is a well-known parkinsonigen toxin in humans. More recently, it has been shown that dithiocarbamates can also induce extrapyramidal syndromes. The biochemical effects of manganese and dithiocarbamates are reviewed and their possible neurotoxic mechanisms are discussed. Both of these components may have played a role in this case.
G Meco; V Bonifati; N Vanacore; E Fabrizio
Related Documents :
23722146 - Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature.
15158666 - The role of sulfatide in thrombogenesis and haemostasis.
15317326 - Aquagenic urticaria: report of a case.
23118636 - Nephrotoxicity with combination vancomycin-aminoglycoside therapy.
23098616 - Recombinant human bone morphogenetic protein 2: adverse events reported to the manufact...
16810146 - Eastern equine encephalitis--new hampshire and massachusetts, august-september 2005.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of work, environment & health     Volume:  20     ISSN:  0355-3140     ISO Abbreviation:  Scand J Work Environ Health     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-26     Completed Date:  1995-01-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7511540     Medline TA:  Scand J Work Environ Health     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  301-5     Citation Subset:  IM    
Department of Neurosciences, La Sapienza University, Rome, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Maneb / adverse effects*
Manganese / adverse effects*
Middle Aged
Occupational Exposure / adverse effects*
Parkinson Disease, Secondary / chemically induced*
Reg. No./Substance:
12427-38-2/Maneb; 7439-96-5/Manganese

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Noise exposure, noise annoyance, use of hearing protection devices and distress among blue-collar wo...
Next Document:  Erythropoietin-independent colonies of red blood cells and leukocytosis in a worker exposed to low l...