Document Detail


Parkes Weber or Klippel-Trenaunay syndrome? Non-invasive diagnosis with MR projection angiography.
MedLine Citation:
PMID:  15007616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Klippel-Trenaunay and Parkes Weber (Klippel-Trenaunay-Weber) syndromes consist of vascular malformations of the capillary, venous and lymphatic systems combined with soft tissue and bone hypertrophy of the affected extremity. Klippel-Trenaunay syndrome is a pure low-flow condition, while Parkes Weber syndrome is characterized by significant arteriovenous fistulas. The distinction of both entities is relevant, since the prognosis and therapeutic strategies differ significantly. Our purpose is to demonstrate that thick-slice dynamic magnetic resonance projection angiography (MRPA) is a non-invasive tool to detect arteriovenous shunting in Parkes Weber syndrome. Four patients underwent MR imaging and MRPA. MRPA demonstrated arteriovenous shunting in three patients. Arteriovenous shunting was characterized by early appearing draining veins. The time of arrival between normal arteries and pathological veins varied between less than 0.5 and 1.0 s. Therefore, the diagnosis in these cases could be specified as Parkes Weber syndrome. In all these cases, arteriovenous shunting was confirmed by intraarterial digital subtraction angiography. One patient showed normal results in MRPA and could be diagnosed as having Klippel-Trenaunay syndrome.
Authors:
S Ziyeh; J Spreer; J Rössler; R Strecker; A Hochmuth; M Schumacher; J Klisch
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2004-03-06
Journal Detail:
Title:  European radiology     Volume:  14     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-10-25     Completed Date:  2005-03-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  2025-9     Citation Subset:  IM    
Affiliation:
Section of Neuroradiology, Neurocenter, University of Freiburg, Breisacher Strasse 64, 79106 Freiburg, Germany. ziyeh@nz.ukl.uni-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Arteriovenous Fistula / diagnosis*,  therapy
Child
Contrast Media / administration & dosage
Diagnosis, Differential
Embolization, Therapeutic / methods
Extremities / blood supply,  pathology
Female
Humans
Klippel-Trenaunay-Weber Syndrome / diagnosis*
Magnetic Resonance Angiography / methods*
Male
Meglumine / analogs & derivatives*,  diagnostic use
Organometallic Compounds / diagnostic use
Thorax / blood supply,  pathology
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine

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