Document Detail

Parietal substrates for dimensional effects in visual search: evidence from lesion-symptom mapping.
MedLine Citation:
PMID:  23404335     Owner:  NLM     Status:  MEDLINE    
In visual search, the detection of pop-out targets is facilitated when the target-defining dimension remains the same compared with when it changes across trials. We tested the brain regions necessary for these dimensional carry-over effects using a voxel-based morphometry study with brain-lesioned patients. Participants had to search for targets defined by either their colour (red or blue) or orientation (right- or left-tilted), and the target dimension either stayed the same or changed on consecutive trials. Twenty-five patients were categorized according to whether they showed an effect of dimensional change on search or not. The two groups did not differ with regard to their performance on several working memory tasks, and the dimensional carry-over effects were not correlated with working memory performance. With spatial, sustained attention and working memory deficits as well as lesion volume controlled, damage within the right inferior parietal lobule (the angular and supramarginal gyri) extending into the intraparietal sulcus was associated with an absence of dimensional carry-over (P < 0.001, cluster-level corrected for multiple comparisons). The data suggest that these regions of parietal cortex are necessary to implement attention shifting in the context of visual dimensional change.
Sandra Utz; Glyn W Humphreys; Magdalena Chechlacz
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2013-02-11
Journal Detail:
Title:  Brain : a journal of neurology     Volume:  136     ISSN:  1460-2156     ISO Abbreviation:  Brain     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-25     Completed Date:  2013-04-23     Revised Date:  2014-03-06    
Medline Journal Info:
Nlm Unique ID:  0372537     Medline TA:  Brain     Country:  England    
Other Details:
Languages:  eng     Pagination:  751-60     Citation Subset:  AIM; IM    
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MeSH Terms
Aged, 80 and over
Attention / physiology*
Brain Injuries / physiopathology*
Brain Mapping*
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging
Middle Aged
Parietal Lobe / physiology*
Space Perception / physiology*
Young Adult
Grant Support
BB/E006175/1/BB/FDA HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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