| Parental decisions regarding a prenatally detected fetal chromosomal abnormality and the impact of genetic counseling: an analysis of 38 cases with aneuploidy in Southeast Turkey. | |
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MedLine Citation:
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PMID: 20119701 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study investigated parental decision-making to terminate or continue a pregnancy after prenatal diagnosis of a chromosomal abnormality among a sample of patients in Southeast Turkey. Between 2004 and 2007, 1068 amniocentesis tests were performed in the Medical Biology and Genetic Department Laboratory at Dicle University. Aneuploidy was found in 38 cases (3.56%). Genetic counseling was provided for the couples that received abnormal results, and they were later interviewed and asked if they had continued or interrupted the pregnancy after the diagnosis. When confronted with autosomal aneuploidy in which a severe prognosis was expected, 85% of cases decided to terminate the pregnancy. When confronted with sex chromosome aneuploidy with a low risk of an abnormal clinical phenotype 60% of cases decided to continue the pregnancy. Among the diagnoses with aneuploidy, pregnancy was continued in 21.1% of cases due to religious beliefs regardless of whether there was a low or severe risk of an abnormal clinical phenotype. These findings indicate that both severity of abnormality and religiosity play an important role in genetic counseling patients' decision-making processes and outcomes in Turkey. In addition, the findings suggest the need for legislation that reduces the differences in approaches between the physicians and institutions regarding parental decision-making to terminate or continue a pregnancy in our country. |
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Authors:
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Mahmut Balkan; Sevgi Kalkanli; Halit Akbas; Ahmet Yalinkaya; M Nail Alp; Turgay Budak |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2010-01-30 |
Journal Detail:
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Title: Journal of genetic counseling Volume: 19 ISSN: 1573-3599 ISO Abbreviation: J Genet Couns Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-24 Completed Date: 2010-09-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9206865 Medline TA: J Genet Couns Country: United States |
Other Details:
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Languages: eng Pagination: 241-6 Citation Subset: IM |
Affiliation:
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Department of Medical Biology and Genetic, Medical Faculty, University of Dicle, 21280 Diyarbakir, Turkey. balkanmah@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Eugenic
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psychology Adult Amniocentesis Aneuploidy* Chromosome Aberrations Cross-Cultural Comparison* Decision Making* Female Genetic Counseling / psychology* Humans Interview, Psychological Male Maternal Age Parents / psychology* Pregnancy Pregnancy Trimester, Second Socioeconomic Factors Turkey Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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